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Phyllis Pease was educated at West Bridgford Grammar School and subsequently at Birmingham University UK, where she was appointed to the academic staff, of the Department of Bacteriology on gaining her Ph.D., much of which was based on electron-microscopy carried out personally by Dr. Pease thus giving her considerable expertise in this area. Her research work was carried out mostly at the Medical School attached to the University and her particular interest has been in the life‑cycles of bacteria and the possible role of their sub‑microscopic (cryptic) forms in human autoimmune and malignant diseases. This work was greatly facilitated by the considerable expansion that took place in the 60s resulting in several new clinical research facilities being added to the existing Faculty of Medicine. Thus she was able to work with the scientists and clinicians attached to these new Departments, whose emphasis was on attempts to elucidate the cause and cure of immunopathologies such as Rheumatoid Arthritis and related conditions. The addition of a Virology Section to the Bacteriology enabled more collaboration to take place. Arguably the greatest contribution here provided by Dr. Pease’ group was the monitoring of the virologist’s tissue cultures for the insidious invasion of them by mycoplasmas, whose cell-killing activities had hitherto often been ascribed to viruses under investigation. She has published some seventy papers on the possible role of bacteria and their sub-cellular elements in immunopathologies in particular as well as some other topics and has delivered papers, by invitation, at several International meetings.
Degrees B.Sc hons (Bacteriology), PhD (Bacteriology) D.Sc (Virology and Bacteriology) Selected Publications: Pease, P.E. (1956). The gonidial stages in Spirillum spp. and Vibrio spp. Journal of General Microbiology, 14: 672-675 Pease, P.E. (1957). The electron microscopy of L-forms induced by penicillin in Proteus vulgaris. Journal of General Microbiology, 17: 66-7 Pease, P.E., Rogers, K.B. and Cole, B.C. (1967). A cytopathogenic strain of Mycoplasma hominis type 1, isolated from the lung of a stillborn infant. J. Path. Bact. 94: 460-2 Pease, P.E. (1969). Discussion paper read by invitation at conference on unusual isolates from clinical material, in the section on micro-organisms associated with malignancy. Annals of New York Academic Sciences, 174: 782-5. Bartlett, L.R. and Pease, P.E. (1975). Latent Haemobartonella muris infection: its transmission and decline in an inbred, ectoparasite-free strain of Wistar rat. Parasitology, 71: 35-40 Pease, P.E. (1979). Observations on L-forms of Yersinia enterocolitica. Journal of Medical Microbiology. 12: 337-46 Pease, PE, England, J., Tyler, R. and Mackintosh, P. (1980). HLA-B27 Yersinia enterocolitica and ankylosing spondylitis. Annals of Rheumatic Diseases, 39: 415-416 Pease, PE, Bartlett, L.R. and Farr, M. (1981). Incorporation of 14C-thymidine by cultures of erythrocytes from rheumatoid arthritis patients and normal subjects, suggesting the presence of an L-form. Experientia, 37: 513 -5 Pease, P.E. (1981). Scanning electron microscopy of L-forms Yersinia enterocolitica. Microbios, 31:17-23 Mackintosh, P. and Pease, P.E. (1982). HLA-B27 Ankylosing spondylitis and some normal rabbit sera. Annals of Rheumatic Diseases. 41: 433-4 Allan, R.,A, Ibbotson, J. and Pease, P.E. (1986) Clustering of Crohn's disease in a Cotswold village. Quarterly Journal of Medicine, 229: 473-8 Pease, PE, Lawson, J., Bartlett, R.L. Lane, MR, Chahal, H., and Tallack, J.E. (1989). Observations on L- forms of Pseudomonas maltophilia. Microbios, 57: 21-6 Pease, P.E. and Tallack, J. E. (1990). A permanent endoparasite of man - I. The silent zoogleal/symposium/L-form phase. Microbios. 64: 173-80 |
